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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 281983Generated: October 29, 2026

3-Bromo-1-methyl-1,2-dihydropyridin-2-one → 8-(1-Methyl-2-oxo-3-pyridinyl)-2-[4-(1,1,1-trifluoropropan-2-yloxy)phenyl]-2,8-diazaspiro[4.5]decan-1-one

https://huagongshe.com/reaction/281983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-1-methyl-1,2-dihydropyridin-2-oneHCID 13024025—
Reactant2-[4-(1,1,1-Trifluoropropan-2-yloxy)phenyl]-2,8-diazaspiro[4.5]decan-1-oneHCID 67226885—
Product8-(1-Methyl-2-oxo-3-pyridinyl)-2-[4-(1,1,1-trifluoropropan-2-yloxy)phenyl]-2,8-diazaspiro[4.5]decan-1-oneHCID 76388503—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-367be13748bc4f4597e1e5b8d8719dfd
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)