HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol | HCID 9794153 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethene | HCID 18936291 | — |
Reaction Steps
1-(3-Furyl)-1-(4-methyl-5-oxazolyl)ethanol (900 mg) in dry chloroform was treated with 1M anhydrous hydrogen chloride in diethylether (1.1 equivalents). After 10 minutes at room temperature, aqueous sodium hydrogen carbonate was added and the mixture was extracted with dichloromethane. The material thus obtained was purified by flash chromatography to give the title compound as an almost colourless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05731335 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-f8ae87d4cdb04743b3be2fcbfdc05511 |
| Source note | uspto-grants-1998_03 |