1,2-Dimethoxyethane → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

HRID 282117Notes

Reaction equation

HRID 282117 reaction equation
[CH3:33][O:34][CH2:35][CH2:36][O:37][CH3:38].[NH2:1][c:2]1[n:3][c:4]([C:18]2=[CH:22][CH2:21][CH2:20][O:19]2)[c:5]([C:16]#[N:17])[c:6]([O:8][S:9]([C:10]([F:11])([F:12])[F:13])(=[O:14])=[O:15])[n:7]1.[c:23]1([NH:29][CH2:30][CH2:31][NH2:32])[cH:24][cH:25][cH:26][cH:27][cH:28]1>>[NH2:1][c:2]1[n:3][c:4]([C:18]2=[CH:22][CH2:21][CH2:20][O:19]2)[c:5]([C:16]#[N:17])[c:6]([NH:32][CH2:31][CH2:30][NH:29][c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[n:7]1

Participants

4

Reactant 3

HCID 80711,2-DimethoxyethaneHCID 742701,2-Ethanediamine, N1-phenyl-HCID 86583757Trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester

Product 1

HCID 185074712-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

Sources & evidence

ORD record
ord-d435662a214a4e558281cfaf3f2e94ba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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