Carbamic acid,n-[2-amino-5-(dimethylamino)-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → (RS)-[5-Dimethylamino-2-(3-oxo-3-{3-[3-(tetrahydro-pyran-2-yloxymethyl)-isoxazol-5-yl]-phenyl}-propionylamino)-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:21])[cH:10][c:11]([C:17]([F:18])([F:19])[F:20])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:22].[C:23]([CH3:25])([CH3:26])([O:27][C:28](=[O:24])[CH2:29][C:30]([c:31]1[cH:32][c:33](-[c:37]2[cH:38][c:39]([CH2:42][O:43][CH:44]3[O:45][CH2:46][CH2:47][CH2:48][CH2:49]3)[n:40][o:41]2)[cH:34][cH:35][cH:36]1)=[O:50])[CH3:51]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:21][C:28](=[O:27])[CH2:29][C:30]([c:31]2[cH:32][c:33](-[c:37]3[cH:38][c:39]([CH2:42][O:43][CH:44]4[O:45][CH2:46][CH2:47][CH2:48][CH2:49]4)[n:40][o:41]3)[cH:34][cH:35][cH:36]2)=[O:50])[cH:10][c:11]([C:17]([F:18])([F:19])[F:20])[c:12]([N:14]([CH3:15])[CH3:16])[cH:13]1)=[O:22]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5a80a9cc8bec4f34910a5228b9fe825e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…