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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 282661Generated: October 26, 2026

Trifluoroacetic acid → rac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (2-methoxy-4-nitro-phenyl)-amide

https://huagongshe.com/reaction/282661

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant2-Methoxy-4-nitroanilineHCID 7337—
ReactantDiphenylphosphinic chlorideHCID 73910—
ReactantDiisopropylethylamineHCID 81531—
Reactantrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acidHCID 66625245—
Productrac-(2'S,3'R,4'S,5'R)-6-chloro-4'-(3-chloro-2-fluoro-phenyl)-2'-(2,2-dimethyl-propyl)-2-oxo-1,2-dihydro-spiro[indole-3,3'-pyrrolidine]-5'-carboxylic acid (2-methoxy-4-nitro-phenyl)-amideHCID 75985747—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-82efc162996a4df3a38b5c6297c1a816
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)