5-Cyano-2-fluorobenzaldehyde → 3-((4-(6-Chlorothieno[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl)methyl)-4-fluorobenzonitrile

HRID 282746Notes

Reaction equation

HRID 282746 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[NH:10][CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)[s:17]1.[F:18][c:19]1[c:20]([CH:27]=[O:28])[cH:21][c:22]([C:23]#[N:24])[cH:25][cH:26]1>>[Cl:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7][n:8][c:9]2[NH:10][CH:11]2[CH2:12][CH2:13][N:14]([CH2:27][c:20]3[c:19]([F:18])[cH:26][cH:25][c:22]([C:23]#[N:24])[cH:21]3)[CH2:15][CH2:16]2)[s:17]1

Participants

3

Reactant 2

HCID 109097255-Cyano-2-fluorobenzaldehydeHCID 579331476-chloro-N-(piperidin-4-yl)thieno[2,3-d]pyrimidin-4-amine

Product 1

HCID 116470293-((4-(6-Chlorothieno[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl)methyl)-4-fluorobenzonitrile

Sources & evidence

ORD record
ord-6883a2cd660443889f2d608575123b92
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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