Isoquinoline-1-carboxylic acid → Tert-butyl 3-[(isoquinoline-1-carbonylamino)methyl]-2-azabicyclo[3.1.0]hexane-2-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH2:15].[c:16]1([C:26](=[O:27])[OH:28])[n:17][cH:18][cH:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]2[CH2:10][CH:11]2[CH2:12][CH:13]1[CH2:14][NH:15][C:26]([c:16]1[n:17][cH:18][cH:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]12)=[O:27]Participants
3
Sources & evidence
- ORD record
- ord-e8f224559d244a76b8a23f646e82ce0e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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