Methanol → Methyl 2-tert-butyl-5-nitro-1H-indole-7-carboxylate

HRID 282800Notes

Reaction equation

HRID 282800 reaction equation
[C:5]([CH3:6])([CH3:7])([CH3:8])[c:9]1[nH:10][c:11]2[c:12]([C:21](=[O:22])[OH:23])[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][c:16]2[cH:17]1.[CH3:24][OH:25].[S:1]([Cl:2])([Cl:3])=[O:4]>>[C:5]([CH3:6])([CH3:7])([CH3:8])[c:9]1[nH:10][c:11]2[c:12]([C:21](=[O:22])[O:23][CH3:24])[cH:13][c:14]([N+:18](=[O:19])[O-:20])[cH:15][c:16]2[cH:17]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 534211852-Tert-butyl-5-nitro-1H-indole-7-carboxylic acid

Product 1

HCID 53436897Methyl 2-tert-butyl-5-nitro-1H-indole-7-carboxylate

Sources & evidence

ORD record
ord-389c1bdc880a44eab8f8490cf554829e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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