Dichloromethane → 8-Allyl-1-ethyl-7-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid methyl ester

HRID 282915Notes

Reaction equation

HRID 282915 reaction equation
[CH3:1][O:2][C:3]([CH2:4][C:5]1([CH2:27][CH3:28])[O:6][CH2:7][CH2:8][c:9]2[c:10]1[nH:11][c:12]1[c:13]([CH2:19][CH:20]([CH2:21][Si:23]([CH3:24])([CH3:25])[CH3:26])[OH:22])[c:14]([F:18])[cH:15][cH:16][c:17]21)=[O:29].[Cl:30][CH2:31][Cl:32]>>[CH3:1][O:2][C:3]([CH2:4][C:5]1([CH2:27][CH3:28])[O:6][CH2:7][CH2:8][c:9]2[c:10]1[nH:11][c:12]1[c:13]([CH2:19][CH:20]=[CH2:21])[c:14]([F:18])[cH:15][cH:16][c:17]21)=[O:29]

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 53662750methyl 2-[1-ethyl-7-fluoro-8-(2-hydroxy-3-trimethylsilylpropyl)-4,9-dihydro-3H-pyrano[3,4-b]indol-1-yl]acetate

Product 1

HCID 147700108-Allyl-1-ethyl-7-fluoro-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid methyl ester

Sources & evidence

ORD record
ord-6284cff1fa27492c9337d70682ed75fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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