1-(2,4-Difluorophenyl)piperazine → N-(1-(4-((4-(2,4-difluorophenyl)piperazin-1-yl)methyl)phenyl)propyl)acetamide

HRID 282918Notes

Reaction equation

HRID 282918 reaction equation
[Cl:15][CH2:16][c:17]1[cH:18][cH:19][c:20]([CH:23]([CH2:24][CH3:25])[NH:26][C:27]([CH3:28])=[O:29])[cH:21][cH:22]1.[F:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3]([N:9]2[CH2:10][CH2:11][N:12]([CH2:16][c:17]3[cH:18][cH:19][c:20]([CH:23]([CH2:24][CH3:25])[NH:26][C:27]([CH3:28])=[O:29])[cH:21][cH:22]3)[CH2:13][CH2:14]2)[cH:4][cH:5][c:6]([F:8])[cH:7]1

Participants

3

Reactant 2

HCID 27346371-(2,4-Difluorophenyl)piperazineHCID 18423118N-(1-(4-chloromethylphenyl)propyl)acetamide

Product 1

HCID 11523910N-(1-(4-((4-(2,4-difluorophenyl)piperazin-1-yl)methyl)phenyl)propyl)acetamide

Sources & evidence

ORD record
ord-ccbba6f7a76648399bb02070535821eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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