Acetic Acid → 2-(5-amino-4,6-dimethylpyrimidine-2-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide

HRID 282997Notes

Reaction equation

HRID 282997 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]([CH2:16][NH:17][c:18]2[n:19][c:20]([CH3:28])[c:21]([N+:25]([O-:26])=[O:27])[c:22]([CH3:24])[n:23]2)=[O:29])[CH3:30])[CH2:12][CH2:13]1.[CH3:31][C:32](=[O:33])[OH:34].[Zn:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([N:14]([C:15]([CH2:16][NH:17][c:18]2[n:19][c:20]([CH3:28])[c:21]([NH2:25])[c:22]([CH3:24])[n:23]2)=[O:29])[CH3:30])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 23994ZincHCID 59336190N-(1-benzylpiperidine-4-yl)-2-(4,6-dimethyl-5-nitropyrimidine-2-ylamino)-N-methylacetamide

Product 1

HCID 251208392-(5-amino-4,6-dimethylpyrimidine-2-ylamino)-N-(1-benzylpiperidine-4-yl)-N-methylacetamide

Sources & evidence

ORD record
ord-1fea9fa061d04f04b085281d08714f39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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