1-Methoxy-2,2,6,6-tetramethyl-piperidin-4-ol → 1-Methoxy-2,2,6,6-tetramethylpiperidin-4-yl 3-(5-Chlorobenzotriazol-2-yl)-5-tert-butyl-4-hydroxyhydrocinnamate

HRID 28324Notes

Reaction equation

HRID 28324 reaction equation
[Cl:1][C:2]1[CH:26]=[CH:25][C:5]2=[N:6][N:7]([C:9]3[CH:10]=[C:11]([CH:17]=[C:18]([C:21]([CH3:24])([CH3:23])[CH3:22])[C:19]=3[OH:20])[CH2:12][CH2:13][C:14]([OH:16])=[O:15])[N:8]=[C:4]2[CH:3]=1.[CH3:27][O:28][N:29]1[C:34]([CH3:36])([CH3:35])[CH2:33][CH:32](O)[CH2:31][C:30]1([CH3:39])[CH3:38]>>[Cl:1][C:2]1[CH:26]=[CH:25][C:5]2=[N:6][N:7]([C:9]3[CH:10]=[C:11]([CH:17]=[C:18]([C:21]([CH3:22])([CH3:23])[CH3:24])[C:19]=3[OH:20])[CH2:12][CH2:13][C:14]([O:16][CH:32]3[CH2:33][C:34]([CH3:35])([CH3:36])[N:29]([O:28][CH3:27])[C:30]([CH3:39])([CH3:38])[CH2:31]3)=[O:15])[N:8]=[C:4]2[CH:3]=1

Participants

3

Reactant 2

HCID 109977701-Methoxy-2,2,6,6-tetramethyl-piperidin-4-olHCID 180087183-(5-Chlorobenzotriazol-2-yl)-5-tert-butyl-4-hydroxyhydrocinnamic acid

Product 1

HCID 101872641-Methoxy-2,2,6,6-tetramethylpiperidin-4-yl 3-(5-Chlorobenzotriazol-2-yl)-5-tert-butyl-4-hydroxyhydrocinnamate

Procedure

3-(5-Chlorobenzotriazol-2-yl)-5-tert-butyl-4-hydroxyhydrocinnamic acid (12.0 g, 0.032 mol) and 1-methoxy-2,2,6,6-tetramethyl-4-hydroxypiperidine (6.66 g, 0.036 mol) are reacted together according to the procedure given in Example 3. The title compound is obtained in a yield of 8.79 g (50.5%) as a light yellow solid, melting at 132-137° C., whose structure is consistent with 1Hnmr and mass spectrometry. The compound has a molar absorptivity of 17,210 l/mole cm.

Sources & evidence

ORD record
ord-3d50e7e410914d55bf1150f6d833304a
Source dataset
uspto-grants-2008_09
Patent number
US07419513B2

Reaction notes

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