Dichloromethane → N-tert-Butyl-3-((4-(3-fluoro-4-(3-(2-fluorophenyl)ureido)benzoyl)piperazin-1-yl)methyl)benzamide
Reaction equation
[Cl:41][CH2:42][Cl:43].[F:31][c:32]1[c:33]([N:38]=[C:39]=[O:40])[cH:34][cH:35][cH:36][cH:37]1.[NH2:1][c:2]1[c:3]([F:30])[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([CH2:14][c:15]3[cH:16][c:17]([C:18](=[O:19])[NH:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26][cH:27]3)[CH2:12][CH2:13]2)[cH:28][cH:29]1>>[NH:1]([c:2]1[c:3]([F:30])[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([CH2:14][c:15]3[cH:16][c:17]([C:18](=[O:19])[NH:20][C:21]([CH3:22])([CH3:23])[CH3:24])[cH:25][cH:26][cH:27]3)[CH2:12][CH2:13]2)[cH:28][cH:29]1)[C:39]([NH:38][c:33]1[c:32]([F:31])[cH:37][cH:36][cH:35][cH:34]1)=[O:40]Participants
4
Sources & evidence
- ORD record
- ord-85456fb2d34d464fb703a37e9935c957
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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