7-[2-(1H-indol-5-yloxy)-ethyl]-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester → 7-{2-[1-(1-Biphenyl-4-yl-2-ethoxycarbonyl-vinyl)-1H-indol-5-yloxy]-ethyl}-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH2:11][c:12]2[cH:13][cH:14][c:15]([CH2:18][CH2:19][O:20][c:21]3[cH:22][c:23]4[cH:24][cH:25][nH:26][c:27]4[cH:28][cH:29]3)[n:16][c:17]21.[CH2:30]([CH3:31])[O:32][C:33]([CH:34]=[C:35]([Cl:36])[c:37]1[cH:38][cH:39][c:40](-[c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[cH:41][cH:42]1)=[O:49]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH2:11][c:12]2[cH:13][cH:14][c:15]([CH2:18][CH2:19][O:20][c:21]3[cH:22][c:23]4[cH:24][cH:25][n:26]([C:35](=[CH:34][C:33]([O:32][CH2:30][CH3:31])=[O:49])[c:37]5[cH:38][cH:39][c:40](-[c:43]6[cH:44][cH:45][cH:46][cH:47][cH:48]6)[cH:41][cH:42]5)[c:27]4[cH:28][cH:29]3)[n:16][c:17]21Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-539182b1a40f4ffeb599e45f17b9cebc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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