Methanol → 6-(3-Acetylamino-1-pyrrolidinyl)-2-(2,4-difluorophenylamino)-5-fluoronicotinic acid
Reaction equation
[C:3]([CH3:4])(=[O:5])[NH:6][CH:7]1[CH2:8][N:9]([c:12]2[n:13][c:14]([NH:23][c:24]3[c:25]([F:31])[cH:26][c:27]([F:30])[cH:28][cH:29]3)[c:15]([C:16](=[O:17])[O:18][CH3:19])[cH:20][c:21]2[F:22])[CH2:10][CH2:11]1.[CH3:1][OH:2].[Na+:33].[OH-:32].[OH2:34]>>[C:3]([CH3:4])(=[O:5])[NH:6][CH:7]1[CH2:8][N:9]([c:12]2[n:13][c:14]([NH:23][c:24]3[c:25]([F:31])[cH:26][c:27]([F:30])[cH:28][cH:29]3)[c:15]([C:16](=[O:17])[OH:18])[cH:20][c:21]2[F:22])[CH2:10][CH2:11]1Participants
6
Sources & evidence
- ORD record
- ord-ac543b711d97441181b04d8c500a2efc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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