Dimethylamine → Methyl 2-chloro-6-(dimethylamino)-5-fluoronicotinate

HRID 283996Notes

Reaction equation

HRID 283996 reaction equation
[CH3:14][NH:15][CH3:16].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([F:13])[c:10]([Cl:12])[n:11]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([F:13])[c:10]([N:15]([CH3:14])[CH3:16])[n:11]1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 2775354Methyl 2,6-dichloro-5-fluoronicotinate

Product 1

HCID 23112242Methyl 2-chloro-6-(dimethylamino)-5-fluoronicotinate

Sources & evidence

ORD record
ord-e892d348fca349e980c9dddba5cdfbb9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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