4-Fluorobenzyl bromide → 4-(2-chloro-9-(4-fluorobenzyl)-9H-purin-6-yl)morpholine
Reaction equation
[Br:17][CH2:18][c:19]1[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]1.[Cl:1][c:2]1[n:3][c:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[n:6][cH:7][nH:8][c:9]2[n:10]1>>[Cl:1][c:2]1[n:3][c:4]([N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[c:5]2[n:6][cH:7][n:8]([CH2:18][c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[c:9]2[n:10]1Participants
3
Sources & evidence
- ORD record
- ord-92ba6b1ee3f34a48afdf57b310712ab5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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