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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 284147Generated: October 29, 2026

3,4-Difluorophenol → 2-(3,4-Difluorophenoxy)-4-cyclohexyloxy-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidine

https://huagongshe.com/reaction/284147

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-DifluorophenolHCID 75927—
Reactant2-(Methylsulfonyl)-4-(cyclohexyloxy)-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidineHCID 69197999—
ReactantButyllithiumHCID 178418339—
Product2-(3,4-Difluorophenoxy)-4-cyclohexyloxy-5-(4-chlorophenyl)-6-(2,4-dichlorophenyl)pyrimidineHCID 10325524—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-4867ccaa5dfd4ad5be7b0ebaae1d76b8
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)