Ethanol → N-(3-Cyanophenyl)-N'-(piperidin-4-yl)cycloheptylurea

HRID 284155Notes

Reaction equation

HRID 284155 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][c:5]([N:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15][N:16]([CH2:19][c:20]3[cH:21][cH:22][cH:23][cH:24][cH:25]3)[CH2:17][CH2:18]2)[CH:26]2[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[cH:6][cH:7][cH:8]1.[CH2:36]1[CH2:37][CH:38]=[CH:39][CH2:40][CH2:41]1.[CH3:33][CH2:34][OH:35].[OH-:42].[OH-:44].[Pd+2:43]>>[C:1](#[N:2])[c:3]1[cH:4][c:5]([N:9]([C:10](=[O:11])[NH:12][CH:13]2[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]2)[CH:26]2[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[cH:6][cH:7][cH:8]1

Participants

6

Reactant 5

HCID 702EthanolHCID 961Hydroxide2×HCID 8079CyclohexeneHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 53879433N-(3-Cyanophenyl)-N'-(1-benzylpiperidin-4-yl)cycloheptylurea

Product 1

HCID 54268872N-(3-Cyanophenyl)-N'-(piperidin-4-yl)cycloheptylurea

Sources & evidence

ORD record
ord-ed59a87c65bd4bd18ed4e14b1337bcc0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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