Potassium Cation → 4-Chloro-5-(4-(trifluoromethyl)phenyl)-N-(3-hydroxyphenyl)isoxazole-3-carboxamide

HRID 284347Notes

Reaction equation

HRID 284347 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[Cl:1][c:2]1[c:3]([C:17](=[O:18])[Cl:19])[n:4][o:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1.[Cl:34][CH2:35][Cl:36].[K+:32].[K+:33].[NH2:20][c:21]1[cH:22][cH:23][cH:24][c:25]([OH:26])[cH:27]1>>[Cl:1][c:2]1[c:3]([C:17](=[O:18])[NH:20][c:21]2[cH:22][cH:23][cH:24][c:25]([OH:26])[cH:27]2)[n:4][o:5][c:6]1-[c:7]1[cH:8][cH:9][c:10]([C:13]([F:14])([F:15])[F:16])[cH:11][cH:12]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6344DichloromethaneHCID 115683-AminophenolHCID 19660Carbonate IonHCID 866520834-Chloro-5-(4-(trifluoromethyl)phenyl)isoxazole-3-carbonyl chloride

Product 1

HCID 251816244-Chloro-5-(4-(trifluoromethyl)phenyl)-N-(3-hydroxyphenyl)isoxazole-3-carboxamide

Sources & evidence

ORD record
ord-11120240a7564ed1b0540d0aa365bc60
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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