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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 284435Generated: October 26, 2026

Dimethylformamide → 1-Boc-4-(4-ethynylphenyl)piperazine

https://huagongshe.com/reaction/284435

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantTert-butyl 4-(4-iodophenyl)piperazine-1-carboxylateHCID 2795511—
Product1-Boc-4-(4-ethynylphenyl)piperazineHCID 86658836—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-996b6b7587014690803b3fe5c127ece7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)