HCID 21031298, compound → HCID 21943486, compound

HRID 28448Notes

Reaction equation

HRID 28448 reaction equation
C(OC([NH:11][CH2:12][C@@H:13]([CH2:17][C@H:18]([CH3:25])[CH2:19][CH2:20][CH2:21][CH:22]([CH3:24])[CH3:23])[C:14]([OH:16])=[O:15])=O)C1C=CC=CC=1.[H][H]>>[NH2:11][CH2:12][CH:13]([CH2:17][CH:18]([CH3:25])[CH2:19][CH2:20][CH2:21][CH:22]([CH3:24])[CH3:23])[C:14]([OH:16])=[O:15]

Participants

3

Reactant 2

HCID 21031298HCID 21031298, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21943486HCID 21943486, compoundYield 67.3%

Procedure

2(R)-(Benzyloxycarbonylamino-methyl)-4(R),8-dimethyl-nonanoic acid (0.148 g, 0.566 mmol) was treated with hydrogen in the presence of 20% pd/C to give 0.082 g of 2-aminomethyl-4,8-dimethyl nonanoic acid after filtration and purification via silica gel chromatography (85/15 CH2Cl2/MeOH). m/z 216.3 (M+).

Sources & evidence

ORD record
ord-9b3b65c7d92949b8ad4af785feae668f
Source dataset
uspto-grants-2008_09
Patent number
US07419981B2

Reaction notes

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