4-bromo-3-(6-hydroxy-2,3-dihydro-1-benzofuran-5-yl)-1,3-dihydro-2H-indol-2-one → 4-Bromo-3-(6-hydroxy-2,3-dihydrobenzofuran-5-yl)-3-(hydroxymethyl)indolin-2-one
Reaction equation
[Br:24][c:25]1[c:26]2[c:30]([cH:31][cH:32][cH:33]1)[NH:29][C:28](=[O:34])[CH:27]2[c:35]1[c:36]([OH:44])[cH:37][c:38]2[c:39]([cH:43]1)[CH2:40][CH2:41][O:42]2.[F:1][c:2]1[cH:3][cH:4][c:5]([OH:6])[c:7]([CH:8]2[C:9](=[O:22])[N:16]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[c:11]3[c:10]2[cH:15][cH:14][cH:13][cH:12]3)[cH:23]1>>[CH2:9]([OH:22])[C:27]1([c:35]2[c:36]([OH:44])[cH:37][c:38]3[c:39]([cH:43]2)[CH2:40][CH2:41][O:42]3)[c:26]2[c:25]([Br:24])[cH:33][cH:32][cH:31][c:30]2[NH:29][C:28]1=[O:34]Participants
3
Sources & evidence
- ORD record
- ord-815b69b3602c46e9b826e7bb146b10da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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