反应详情

9 ml (0.05 mol) of 2,2,6-trimethyl-4H-1,3-dioxin-4-one (diketene-acetone adduct) were added dropwise to a solution of 5.5 ml (0.05 mol) of benzylamine in 20 ml of toluene and the temperature was allowed to rise 70° C. The solution was refluxed for 2 h then the solvent was removed in vacuo. The crude product was triturated with ether obtaining 7.5 g of the title compound. M.p.=84°-86° C.

1. customto rise 70° C
2. temperatureThe solution was refluxed for 2 h
3. customthe solvent was removed in vacuo
4. customThe crude product was triturated with ether obtaining 7.5 g of the title compound