HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178418269, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Benzenediazonium chloride | HCID 60992 | — |
| Reactant | 3-Oxo-N,N-di(propan-2-yl)butanamide | HCID 12318541 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178418269 | HCID 178418269 | 68.2% |
Reaction Steps
7.0 g (0.038 mol) of N,N-diisopropyl-3-oxobutyramide, a solution of 5.3 g (0.133 mol) of NaOH in 58 ml of water and 0.04 mol of phenyldiazonium chloride were treated as described in preparation 8. The crude reaction mixture was purified by chromatography on silica gel (hexane/Et2O 95:5) obtaining 7.5 g of the title compound which was used as such in the subsequent step. M.p.=143°-145° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05731322 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-ee71b009ed3f4c28bab5abd1c42abd9d |
| Source note | uspto-grants-1998_03 |