4-Chloroaniline → HCID 11359913, Verbindung

Beteiligte Stoffe

Reaktionsschritte

Following the method described in Example 26, 4-chloro-6-(5-chloro-2-methyl-phenyl)-pyrimidin-2-yl-amine and 4-chloroaniline provided the title compound (78% yield). 1H NMR (DMSO-d6) δ 2.34 (s, 3H, CH3), 6.10 (s, 1H, Ar), 6.45 (s, 2H, NH2), 7.30-7.33 (m, 3H, Ar), 7.37 (dd, 1H, J=8.1 Hz, J=2.3 Hz, Ar), 7.41 (d, 1H, J=2.2 Hz, Ar), 7.80-7.83 (m, 2H, Ar), 9.35 (s, 1H, NH).

Herkunft & Nachweise