4-Bromoaniline → HCID 11257777、化合物

関与物質

役割	名称	HCID	仕込み量
反応物	4-Bromoaniline	HCID 7807	—
反応物	4-Chloro-6-(5-chloro-2-methylphenyl)pyrimidin-2-yl-amine	HCID 86004347	—
生成物	HCID 11257777	HCID 11257777	84%

反応手順

Following the method described in Example 26, 4-chloro-6-(5-chloro-2-methyl-phenyl)-pyrimidin-2-yl-amine and 4-bromoaniline provided the title compound (84% yield). 1H NMR (DMSO-d6) δ 2.35 (s, 3H, CH3), 6.10 (s, 1H, Ar), 6.45 (s, 2H, NH2), 7.31 (d, 1H, J=8.3 Hz, Ar), 7.37 (dd, 1H, J=8.2 Hz, J=2.3 Hz, Ar), 7.41 (d, 1H, J=2.3 Hz, Ar), 7.43-7.45 (m, 2H, Ar), 7.78-7.75 (m, 2H, Ar), 9.35 (s, 1H, NH).

情報源と証拠

DOI	10.6084/m9.figshare.5104873.v1
特許番号	US07419984B2
出典データセット	uspto-grants-2008_09
ORD ID	ord-32b171185695435ba66c8841ccdd4f78
出典メモ	uspto-grants-2008_09