AP-24592 → 2-{4-[5-(4-Methoxy-phenyl)-benzoimidazol-1-yl]-phenyl}-N-[4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

HRID 285460Notes

Reaction equation

HRID 285460 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[c:12]([n:13](-[c:16]4[cH:17][cH:18][c:19]([CH2:22][C:23](=[O:24])[OH:25])[cH:20][cH:21]4)[cH:14][n:15]3)[cH:26][cH:27]2)[cH:7][cH:8]1.[CH3:28][N:29]1[CH2:30][CH2:31][N:32]([CH2:35][c:36]2[c:37]([C:43]([F:44])([F:45])[F:46])[cH:38][c:39]([NH2:42])[cH:40][cH:41]2)[CH2:33][CH2:34]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[cH:10][c:11]3[c:12]([n:13](-[c:16]4[cH:17][cH:18][c:19]([CH2:22][C:23](=[O:25])[NH:42][c:39]5[cH:38][c:37]([C:43]([F:44])([F:45])[F:46])[c:36]([CH2:35][N:32]6[CH2:31][CH2:30][N:29]([CH3:28])[CH2:34][CH2:33]6)[cH:41][cH:40]5)[cH:20][cH:21]4)[cH:14][n:15]3)[cH:26][cH:27]2)[cH:7][cH:8]1

Participants

3

Reactant 2

HCID 46838908AP-24592HCID 67021579{4-[5-(4-Methoxyphenyl)-benzoimidazol-1-yl]-phenyl}-acetic acid

Product 1

HCID 119932882-{4-[5-(4-Methoxy-phenyl)-benzoimidazol-1-yl]-phenyl}-N-[4-(4-methyl-piperazin-1-ylmethyl)-3-trifluoromethyl-phenyl]-acetamide

Sources & evidence

ORD record
ord-a49d231858814fe28a2fce4386b24273
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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