1-(2-(4-Iodophenoxy)ethyl)pyrrolidine → 3-(4-Chloro-phenyl)-6-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylethynyl]-pyridazine
Reaction equation
[Cl:16][c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][n:25][c:26]([C:29]#[CH:30])[cH:27][cH:28]2)[cH:21][cH:22]1.[I:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)[cH:14][cH:15]1>>[c:2]1([C:30]#[C:29][c:26]2[n:25][n:24][c:23](-[c:20]3[cH:19][cH:18][c:17]([Cl:16])[cH:22][cH:21]3)[cH:28][cH:27]2)[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:10][CH2:11][CH2:12][CH2:13]2)[cH:14][cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-be38bdef4cf04506bad8366379ff4383
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…