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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28587Generated: October 27, 2026

2-N-Boc-aminopropionic acid → (S)-2-tert-butoxycarbonylamino-propionic acid 4-[2-amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-benzyl ester

https://huagongshe.com/reaction/28587

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-N-Boc-aminopropionic acidHCID 268471—
ReactantBenzenemethanol, 4-((2-amino-6-(5-chloro-2-ethoxyphenyl)-4-pyrimidinyl)amino)-HCID 10406874—
Product(S)-2-tert-butoxycarbonylamino-propionic acid 4-[2-amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-benzyl esterHCID 68984492—

Reaction Steps

(S)-2-tert-Butoxycarbonylamino-propionic acid 4-[2-amino-6-(5-chloro-2-ethoxy-phenyl)-pyrimidin-4-ylamino]-benzyl ester was prepared according to the method described for Example 64 by using the title compound of Example 44 and 2-tert-butoxycarbonylamino-propionic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419984B2
Source datasetuspto-grants-2008_09
ORD IDord-a0f507f829c340aeb44b4a13984aa950
Source noteuspto-grants-2008_09