3-Chloropropyl 2,4-dimethylphenyl ether → 1-(3-(2,4-Dimethylphenoxy)prop-1-yl)-4-hydroxy-4-(quinolin-3-yl)piperidine
Reaction equation
[CH3:1][c:2]1[c:3]([O:9][CH2:10][CH2:11][CH2:12][Cl:13])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1.[OH:14][C:15]1([c:21]2[cH:22][n:23][c:24]3[cH:25][cH:26][cH:27][cH:28][c:29]3[cH:30]2)[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1>>[CH3:1][c:2]1[c:3]([O:9][CH2:10][CH2:11][CH2:12][N:18]2[CH2:17][CH2:16][C:15]([OH:14])([c:21]3[cH:22][n:23][c:24]4[cH:25][cH:26][cH:27][cH:28][c:29]4[cH:30]3)[CH2:20][CH2:19]2)[cH:4][cH:5][c:6]([CH3:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-eb57bb4d4ad64cd9b869d86a5d617bc4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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