2-(Trifluoromethyl)aniline → 4-[(2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)methyl]-N-[2-(trifluoromethyl)phenyl]benzamide
Reaction equation
[CH:12]1([CH2:13][NH2:14])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[F:1][C:2]([c:3]1[c:4]([NH2:5])[cH:6][cH:7][cH:8][cH:9]1)([F:10])[F:11].[O:20]=[C:21]1[N:22]([CH2:41][c:42]2[cH:43][cH:44][c:45]([C:46](=[O:47])[OH:48])[cH:49][cH:50]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][c:28]2[C:29]12[c:30]1[c:31]([cH:34][c:35]3[c:39]([cH:40]1)[CH2:38][CH2:37][O:36]3)[O:32][CH2:33]2.[O:51]=[C:52]1[C:53]2([CH2:54][O:55][c:56]3[cH:57][c:58]4[c:59]([cH:60][c:61]32)[CH2:62][CH2:63][O:64]4)[c:65]2[c:66]([cH:67][cH:68][cH:69][cH:70]2)[N:71]1[CH2:72][c:73]1[cH:74][c:75]([C:79]([OH:80])=[O:81])[cH:76][cH:77][cH:78]1>>[F:1][C:2]([c:3]1[c:4]([NH:5][C:46]([c:45]2[cH:44][cH:43][c:42]([CH2:41][N:22]3[C:21](=[O:20])[C:29]4([c:28]5[c:23]3[cH:24][cH:25][cH:26][cH:27]5)[c:30]3[c:31]([cH:34][c:35]5[c:39]([cH:40]3)[CH2:38][CH2:37][O:36]5)[O:32][CH2:33]4)[cH:50][cH:49]2)=[O:47])[cH:6][cH:7][cH:8][cH:9]1)([F:10])[F:11]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-a4d3c1102e334501a37221e890537143
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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