HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroaniline → HCID 11406630, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroaniline | HCID 7812 | — |
| Reactant | 2-Amino-4-chloro-6-(2-methyl-5-bromo-phenyl)-pyrimidine | HCID 86004341 | — |
| Product | HCID 11406630 | HCID 11406630 | 76% |
Reaction Steps
Following the method described in Example 26, 4-(5-bromo-2-methyl-phenyl)-6-chloro-pyrimidin-2-ylamine and 4-chloro-phenylamine provided the title compound (76% yield). 1H NMR (DMSO-d6) δ 2.35 (s, 3H, CH3), 6.39 (s, 1H, Ar), 7.40 (d, 1H, J=8.4 Hz, Ar), 7.47 (d, 2H, J=8.5 Hz, Ar), 7.70-7.71 (m, 2H, Ar), 7.84-7.89 (m, 2H, Ar), 10.95 (br s, 1H, NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07419984B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-b3578ec648eb4b5bb69ed4b40ddacccf |
| Source note | uspto-grants-2008_09 |