Dichloromethane → N-[1-[4-(3,4-difluorophenoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-5-pyridin-2-ylthiophene-2-sulfonamide

HRID 286064Notes

Reaction equation

HRID 286064 reaction equation
[CH2:16]([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH:23]([C:24](=[O:25])[N:26]1[CH2:27][CH2:28][CH:29]([O:32][c:33]2[cH:34][c:35]([F:40])[c:36]([F:39])[cH:37][cH:38]2)[CH2:30][CH2:31]1)[NH2:41].[Cl:42][CH2:43][Cl:44].[n:1]1[c:2](-[c:7]2[cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[Cl:15])[s:11]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2](-[c:7]2[cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[NH:41][CH:23]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[C:24](=[O:25])[N:26]3[CH2:27][CH2:28][CH:29]([O:32][c:33]4[cH:34][c:35]([F:40])[c:36]([F:39])[cH:37][cH:38]4)[CH2:30][CH2:31]3)[s:11]2)[cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 27372315-(2-Pyridyl)thiophene-2-sulfonyl chlorideHCID 69954213HCID 69954213, compound

Product 1

HCID 69951722N-[1-[4-(3,4-difluorophenoxy)piperidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-5-pyridin-2-ylthiophene-2-sulfonamide

Sources & evidence

ORD record
ord-e65a8a4b66204b60ab6140adc205cd6c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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