Water → N2-Cyclopropylmethyl-5-phenyl-N4-pyridin-2-ylmethyl-thieno[2,3-d]pyrimidine-2,4-diamine

HRID 286098Notes

Reaction equation

HRID 286098 reaction equation
[CH:25]1([CH2:28][NH2:29])[CH2:26][CH2:27]1.[Cl:1][c:2]1[n:3][c:4]([NH:17][CH2:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[c:5]2[c:6]([n:7]1)[s:8][cH:9][c:10]2-[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[OH2:30]>>[c:2]1([NH:29][CH2:28][CH:25]2[CH2:26][CH2:27]2)[n:3][c:4]([NH:17][CH2:18][c:19]2[n:20][cH:21][cH:22][cH:23][cH:24]2)[c:5]2[c:6]([n:7]1)[s:8][cH:9][c:10]2-[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1

Participants

4

Reactant 3

HCID 962WaterHCID 75646CyclopropanemethanamineHCID 865963692-chloro-5-phenyl-N-(pyridin-2-ylmethyl)thieno[2,3-d]pyrimidin-4-amine

Product 1

HCID 86596370N2-Cyclopropylmethyl-5-phenyl-N4-pyridin-2-ylmethyl-thieno[2,3-d]pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-f8dd77b3b17c41538d29777bcfa524e9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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