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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 28612Generated: October 29, 2026

4-Nitrobenzenebutanol → 4-(4-Aminophenyl)butan-1-OL

https://huagongshe.com/reaction/28612

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-NitrobenzenebutanolHCID 590869—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product4-(4-Aminophenyl)butan-1-OLHCID 15006226100%

Reaction Steps

A mixture of 4-(4-nitro-phenyl)-butan-1-ol (2.0 g, 1.02 mmol), palladium on carbon (100 mg, 10%) and ethanol (25 ml) was treated with hydrogen gas on a Parr shaker (50 psi) for 1 hour. The mixture was filtered through a pad of celite under suction and the filtrate was concentrated under reduced pressure to afford 4-(4-amino-phenyl)-butan-1-ol (100% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07419984B2
Source datasetuspto-grants-2008_09
ORD IDord-73353c8d965f4223b88b5cfc96d4a4b7
Source noteuspto-grants-2008_09