1-(4-Nitrophenyl)-2,2,2-trifluoroethane-1,1-diol → 1-(4-Aminophenyl)-2,2,2-trifluoroethan-1-ol

참여 물질

반응 단계

A mixture of 2,2,2-trifluoro-1-(4-nitro-phenyl)-ethane-1,1-diol (1.1 g, 4.6 mmol), palladium on carbon (100 mg, 10%), and ethanol (50 ml) was treated with hydrogen gas on a Parr shaker (50 psi) for 1 hour. The mixture was filtered through celite under suction and the filtrate was concentrated under reduced pressure to afford 1-(4-amino-phenyl)-2,2,2-trifluoro-ethanol (100% yield).

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