DL-leucine → N-(1-amino-4-methyl-1-oxopentan-2-yl)-3-bromo-8-methyl-5,6,7,9-tetrahydroimidazo[1,5-a][1,4]diazepine-1-carboxamide

HRID 286190Notes

Reaction equation

HRID 286190 reaction equation
[Br:1][c:2]1[n:3][c:4]([C:13](=[O:14])[NH:15][CH:16]([C:17](=[O:18])[NH:19][CH3:20])[CH2:21][CH:22]([CH3:23])[CH3:24])[c:5]2[n:6]1[CH2:7][CH2:8][CH2:9][N:10]([CH3:12])[CH2:11]2.[CH3:25][CH:26]([CH2:27][CH:28]([C:29](=[O:30])[OH:31])[NH2:32])[CH3:33].[NH2-:34]>>[Br:1][c:2]1[n:3][c:4]([C:13](=[O:14])[NH:15][CH:16]([C:17](=[O:18])[NH2:19])[CH2:21][CH:22]([CH3:23])[CH3:24])[c:5]2[n:6]1[CH2:7][CH2:8][CH2:9][N:10]([CH3:12])[CH2:11]2

Participants

4

Reactant 3

HCID 857DL-leucineHCID 2826723AzanideHCID 669319173-bromo-8-methyl-N-[4-methyl-1-(methylamino)-1-oxopentan-2-yl]-5,6,7,9-tetrahydroimidazo[1,5-a][1,4]diazepine-1-carboxamide

Product 1

HCID 66931756N-(1-amino-4-methyl-1-oxopentan-2-yl)-3-bromo-8-methyl-5,6,7,9-tetrahydroimidazo[1,5-a][1,4]diazepine-1-carboxamide

Sources & evidence

ORD record
ord-bcb17e7248e74e7fa83feeb8ed1c2d4b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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