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HRID2862

反应详情

EQUATION

反应方程式

HRID 2862 的结构方程式

REACTANTS

反应物

2
结构：BrB(Br)Br
HCID25134

Boron tribromide

BBr3

结构：CCCN(CCC)C(=O)n1cc(C)c2c1C[C@]1(c3cccc(OC)c3)CCN(CC)C[C@H]1C2.Cl
HCID86752326

未命名化合物

PRODUCTS

生成物

1
结构：CCCN(CCC)C(=O)n1cc(C)c2c1C[C@]1(c3cccc(O)c3)CCN(CC)C[C@H]1C2
HCID57276745

未命名化合物

PROCEDURE

实验过程

0.56 g (1.15 mmol) of (±)-trans-dipropylaminocarbonyl-6-ethyl-3-methyl-8a-(3-methoxyphenyl)-4,4a,5,6,7,8,8a,9-octahydro-1H-pyrrolo[2,3-g]isoquinoline hydrochloride were treated with 0.65 ml (7 mmol) of boron tribromide as described in example 2. The residue was purified by flash chromatography (AcOEt/MeOH/conc. NH4OH 75:25:2.5). The crude product was crystallised from acetone yielding 0.075 g of the title compound. M.p.=151°-153° C.

WORKUP

后处理

  1. customThe residue was purified by flash chromatography (AcOEt/MeOH/conc. NH4OH 75:25:2.5)
  2. customThe crude product was crystallised from acetone yielding 0.075 g of the title compound