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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 286228Generated: October 29, 2026

Dimethylformamide → 3-[4-(3-aminopyrrolidine-1-carbonyl)-2-(cyclopropylmethyl)-1-oxoisoquinolin-6-yl]-N-cyclopropyl-4-methylbenzamide

https://huagongshe.com/reaction/286228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
Reactant3-AminopyrrolidineHCID 164401—
Reactant(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 4641409—
Reactant6-(5-(Cyclopropylcarbamoyl)-2-methylphenyl)-2-(cyclopropylmethyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acidHCID 57551760—
Product3-[4-(3-aminopyrrolidine-1-carbonyl)-2-(cyclopropylmethyl)-1-oxoisoquinolin-6-yl]-N-cyclopropyl-4-methylbenzamideHCID 67401264—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-76651f6d391c46cfad88854b5b226c4a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)