Dichloromethane → 2-(Chloromethyl)-5-fluoropyridine

HRID 286282Notes

Reaction equation

HRID 286282 reaction equation
[CH2:14]([Cl:15])[Cl:16].[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][OH:9])[n:6][cH:7]1.[S:10]([Cl:11])([Cl:12])=[O:13]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:8][Cl:12])[n:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 24729312(5-Fluoropyridin-2-yl)methanol

Product 1

HCID 216980592-(Chloromethyl)-5-fluoropyridine

Sources & evidence

ORD record
ord-292b40e117c641dba13fe5d6544a5767
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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