Morpholin-2-ylmethanol → 5-{1-[4-(1-Hydroxy-1-methyl-ethyl)-2-trifluoromethyl-benzyl]-1H-indazol-5-ylmethylene}-2-(2-hydroxymethyl-morpholin-4-yl)-thiazol-4-one
Reaction equation
[CH2:1]([S:2][C:4]1=[N:8][C:7](=[O:9])[C:6](=[CH:10][c:11]2[cH:12][c:13]3[cH:14][n:15][n:16]([CH2:20][c:21]4[c:22]([C:31]([F:32])([F:33])[F:34])[cH:23][c:24]([C:27]([CH3:28])([CH3:29])[OH:30])[cH:25][cH:26]4)[c:17]3[cH:18][cH:19]2)[S:5]1)[CH3:3].[O:35]1[CH:36]([CH2:41][OH:42])[CH2:37][NH:38][CH2:39][CH2:40]1>>[C:4]1([N:38]2[CH2:37][CH:36]([CH2:41][OH:42])[O:35][CH2:40][CH2:39]2)=[N:8][C:7](=[O:9])[C:6](=[CH:10][c:11]2[cH:12][c:13]3[cH:14][n:15][n:16]([CH2:20][c:21]4[c:22]([C:31]([F:32])([F:33])[F:34])[cH:23][c:24]([C:27]([CH3:28])([CH3:29])[OH:30])[cH:25][cH:26]4)[c:17]3[cH:18][cH:19]2)[S:5]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-477cc3a0143040789304b6464a18eb79
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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