3,4-Difluoroaniline → 2-chloro-N4-(3,4-difluorophenyl)-5-fluoro-4-pyrimidineamine

HRID 286777Notes

Reaction equation

HRID 286777 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[F:10][c:11]1[cH:12][c:13]([NH2:14])[cH:15][cH:16][c:17]1[F:18]>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:14][c:13]2[cH:12][c:11]([F:10])[c:17]([F:18])[cH:16][cH:15]2)[n:7]1

Participants

3

Reactant 2

HCID 774693,4-DifluoroanilineHCID 2507052,4-Dichloro-5-fluoropyrimidine

Product 1

HCID 220610492-chloro-N4-(3,4-difluorophenyl)-5-fluoro-4-pyrimidineamine

Sources & evidence

ORD record
ord-55ab35bcf0874a9cb535a13d769348e8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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