5-chloro-6-fluoro-1H-indole-7-carboxylic acid → 5-Chloro-6-fluoro-1H-indole-7-carboxylic acid [2-(3,4-dichloro-phenyl)-ethyl]-(4-tri-methylsilanyl-benzyl)-amide
Reaction equation
[Cl:15][c:16]1[cH:17][c:18]([CH2:23][CH2:24][NH:25][CH2:26][c:27]2[cH:28][cH:29][c:30]([Si:33]([CH3:34])([CH3:35])[CH3:36])[cH:31][cH:32]2)[cH:19][cH:20][c:21]1[Cl:22].[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[c:9]([C:12](=[O:13])[OH:14])[c:10]1[F:11]>>[Cl:1][c:2]1[cH:3][c:4]2[cH:5][cH:6][nH:7][c:8]2[c:9]([C:12](=[O:14])[N:25]([CH2:24][CH2:23][c:18]2[cH:17][c:16]([Cl:15])[c:21]([Cl:22])[cH:20][cH:19]2)[CH2:26][c:27]2[cH:28][cH:29][c:30]([Si:33]([CH3:34])([CH3:35])[CH3:36])[cH:31][cH:32]2)[c:10]1[F:11]Participants
3
Sources & evidence
- ORD record
- ord-6149ed9f0b194604ba7c0277c932ea75
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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