2-Thiopheneacetyl chloride → Ethyl 1-(2-thiopheneacetyl)-6-methyl-3-piperidinecarboxylate
Reaction equation
[C:1]([N:2]1[CH2:3][CH2:4][CH2:5][CH:6]([C:7]([O:8][CH2:9][CH3:10])=[O:11])[CH2:12]1)(=[O:13])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1.[CH3:20][CH:21]1[CH2:22][CH2:23][CH:24]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[CH2:25][NH:26]1.[s:32]1[c:33]([CH2:37][C:38](=[O:39])[Cl:40])[cH:34][cH:35][cH:36]1>>[CH3:20][CH:21]1[CH2:22][CH2:23][CH:24]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[CH2:25][N:26]1[C:38]([CH2:37][c:33]1[s:32][cH:36][cH:35][cH:34]1)=[O:39]Participants
4
Sources & evidence
- ORD record
- ord-2bd4ac03822740bd99bd516e96cf11ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
Loading…