Potassium Cation → Methyl 5-fluoro-2-methylnicotinate

HRID 287015Notes

Reaction equation

HRID 287015 reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[CH2:19]1[O:20][CH2:21][CH2:22][O:23][CH2:24]1.[Cl:1][c:2]1[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([F:12])[cH:10][n:11]1.[K+:17].[K+:18]>>[c:2]1([CH3:13])[c:3]([C:4](=[O:5])[O:6][CH3:7])[cH:8][c:9]([F:12])[cH:10][n:11]1

Participants

5

Reactant 4

HCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 24229209Methyl 2-chloro-5-fluoronicotinate

Product 1

HCID 68863106Methyl 5-fluoro-2-methylnicotinate

Sources & evidence

ORD record
ord-5376d5937f3d49ab8b750860ace95115
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…