Dichloromethane → 4-Bromo-6-trifluoromethyl-2-[4-(3-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-1-(2-trimethylsilanyl-ethoxymethyl)-1H-benzoimidazole
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:27]([F:28])([F:29])[F:30])[cH:5][c:6]2[nH:7][c:8]([N:11]3[CH2:12][CH2:13][N:14]([c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4[C:23]([F:24])([F:25])[F:26])[CH2:15][CH2:16]3)[n:9][c:10]12.[CH3:31][Si:32]([CH2:33][CH2:34][O:35][CH2:36][Cl:37])([CH3:38])[CH3:39].[Cl:40][CH2:41][Cl:42]>>[Br:1][c:2]1[cH:3][c:4]([C:27]([F:28])([F:29])[F:30])[cH:5][c:6]2[n:7]([CH2:36][O:35][CH2:34][CH2:33][Si:32]([CH3:31])([CH3:38])[CH3:39])[c:8]([N:11]3[CH2:12][CH2:13][N:14]([c:17]4[n:18][cH:19][cH:20][cH:21][c:22]4[C:23]([F:24])([F:25])[F:26])[CH2:15][CH2:16]3)[n:9][c:10]12Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-bb9b78ff26d443d99c0123f447282c32
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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