Dichloromethane → 3-[2-{[3-(Diethylamino)propyl]amino)-8-(2,6-difluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylbenzoic acid

HRID 287130Notes

Reaction equation

HRID 287130 reaction equation
[CH2:33]([CH3:34])[N:35]([CH2:36][CH2:37][CH2:38][NH2:39])[CH2:40][CH3:41].[Cl:42][CH2:43][Cl:44].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:32])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([S:29]([CH3:30])=[O:31])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25][cH:26][c:27]2[CH3:28])[c:4]([F:8])[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:32])[cH:11][cH:12][c:13]3[c:14]2[n:15][c:16]([NH:39][CH2:38][CH2:37][CH2:36][N:35]([CH2:33][CH3:34])[CH2:40][CH3:41])[n:17][c:18]3-[c:19]2[cH:20][c:21]([C:22](=[O:23])[OH:24])[cH:25][cH:26][c:27]2[CH3:28])[c:4]([F:8])[cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 61011N,N-Diethyl-1,3-propanediamineHCID 59212699HCID 59212699, compound

Product 1

HCID 574345623-[2-{[3-(Diethylamino)propyl]amino)-8-(2,6-difluorophenyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-4-yl]-4-methylbenzoic acid

Sources & evidence

ORD record
ord-e717384f4cba4528a62a813fdec77ab2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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