Acetate → 1-(3-Bromo-benzyl)-7-trifluoromethyl-1,2,3,4-tetrahydro-quinoline
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][Br:9])[cH:5][cH:6][cH:7]1.[CH3:25][C:26](=[O:27])[O-:28].[CH3:29][CH2:30][OH:31].[F:10][C:11]([c:12]1[cH:13][cH:14][c:15]2[c:20]([cH:21]1)[NH:19][CH2:18][CH2:17][CH2:16]2)([F:22])[F:23].[Na+:24].[OH2:32]>>[Br:1][c:2]1[cH:3][c:4]([CH2:8][N:19]2[CH2:18][CH2:17][CH2:16][c:15]3[cH:14][cH:13][c:12]([C:11]([F:10])([F:22])[F:23])[cH:21][c:20]32)[cH:5][cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-61873716b4964b15af2399a135c6fa68
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (8/10)
Reaction notes
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