Ethanol → Tert-butyl 3-[(3-chlorophenyl)-hydroxy-methyl]piperidine-1-carboxylate

HRID 287434Notes

Reaction equation

HRID 287434 reaction equation
[BH4-:23].[CH3:25][CH2:26][OH:27].[Cl:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[CH:7]2[CH2:8][N:9]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:10][CH2:11][CH2:12]2)[cH:20][cH:21][cH:22]1.[Na+:24]>>[Cl:1][c:2]1[cH:3][c:4]([CH:5]([OH:6])[CH:7]2[CH2:8][N:9]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:10][CH2:11][CH2:12]2)[cH:20][cH:21][cH:22]1

Participants

5

Reactant 4

HCID 702EthanolHCID 923Sodium ionHCID 28123BorohydrideHCID 53420072Tert-butyl 3-(3-chlorobenzoyl)piperidine-1-carboxylate

Product 1

HCID 58011573Tert-butyl 3-[(3-chlorophenyl)-hydroxy-methyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-0ea6b62a7c634c72bb3ee2b9130831f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

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